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bupropion sr bipolar disorder

May 14th, 2018 · post by Phil Chokeword · Make a comment

Wellbutrin should be used with caution in patients with renal impairment and a reduced frequency and or dose should be considered as bupropion and the metabolites of bupropion may accumulate in such patients to a greater extent than usual.

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there has been controversy about whether it is useful to add an antidepressant such as bupropion to a mood stabilizer in people with bipolar depression, but recent reviews have concluded that bupropion in this situation does no significant harm and may sometimes give significant benefit.

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subjects aged 18 75 years, smoking 10 or more cigarettes per day were randomized 1 1 1 1 to chantix 1 mg bid, bupropion sr 150 mg bid, nicotine replacement therapy patch nrt 21 mg day with taper or placebo for a treatment period of 12 weeks; they were then followed for another 12 weeks post-treatment.

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it is a combination of two active substances bupropion and naltrexone already approved for use in the european union eu in other indications.

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bupropion monoamine oxidase inhibitors maois intended to treat psychiatric disorders are contraindicated for use with bupropion or within 14 days of discontinuing treatment with bupropion.


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